Endocrine Abstracts

Fifty-three year old male presented to gastroenterologist with retrosternal pain and dysphagia. On gastroscopy a 2 cm soft sub-pedunculated polypoid mass in the lower oesophagus was identified and on biopsy it was confirmed as adenocarcinoma. CT scan confirmed the finding but additionally identified 20mm right adrenal “incidentaloma” with mild calcification and reassuring imaging characteristics, further supported by a low uptake on 18-FDG PET-CT. He underwent Ivor L...

Primary hyperparathyroidism is rarely diagnosed in pregnancy; not only because it is uncommon in that age group but also because many of the symptoms overlap with non-specific pregnancy symptoms (nausea, vomiting, fatigue, constipation). Primary hyperparathyroidism with significant hypercalcaemia can potentially cause serious maternal (preeclampsia, nephrolithiasis, pancreatitis and hypercalcaemic crisis) and foetal (miscarriage, stillbirth, neonatal hypocalcaemia leading to t...

A 53-year old male presented to his optician with blurring of vision on the right and was diagnosed to have branch retinal vein occlusion. Over the next 6 weeks he manifested further visual impairment, initially due to right central retinal venous occlusion (CRVO) and after another 3 months left CRVO. He received intravitreal Ranibizumab injections and timolol-dorzolamide eye drops in both eyes. Soon after this, he had a hospital admission for infected submandibular gland and ...

Aim: If ‘0’minute salivary cortisol (SALCORT_0) or cortisone (SALCONE_0) can predict normal post-synacthen cortisol response.Method: Baseline salivary sample was collected for 110 patients who had short synacthen test (SST) between 09:00 and 10:00 after hydrocortisone withdrawal for at least 24-hour. SST was labelled ‘pass’ if 30-minute serum cortisol was >450 nmol/l. Serum cortisol was measured by immunoassay whereas salivary cor...

There is scant literature on various mental health parameters following treatment of hyperthyroidism. We present our initial results from an ongoing quality improvement project, jointly undertaken by the Endocrinology and Psychiatry teams.Aim: To evaluate anxiety, depression, ability to work and quality of life (QOL) of patients with hyperthyroidism on presentation and after institution of specific therapy.Method: We assessed 68 ne...